Amr A. Hafez
Department of Surgical Oncology, National Cancer Institute, Cairo University, Egypt
Publications
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Research Article
Efficacy of Different Doses of Photo-Biomodulation on Palmo Plantar Erythrodysesthesia Syndrome Associated with Cancer Therapy
Author(s): Aya M. M. Mohamed*, Eman M. Othman, Karim I. Saafan, Amr A. Hafez, Labib A. Gaber Shami and Maha Abd-ELmonem
Background: Hand-Foot Syndrome (HFS) is a common and debilitating side effect of cancer therapies, particularly those involving capecitabine and 5-Fluorouracil (5-FU). HFS manifests as painful redness, swelling, and tingling on the palms and soles, severely impacting patients’ quality of life. Photobiomodulation (PBM), a non-invasive therapy using light to stimulate cellular healing, has been proposed as an effective treatment for HFS. Previous studies have indicated that the intensity of PBM may influence its therapeutic efficacy, with 2 J/ cm² and 4 J/cm² doses showing promise in reducing HFS symptoms. Purpose: This study aims to compare the efficacy of PBM at two different fluence levels (2 J/cm² and 4 J/ cm²) in reducing the severity of HFS and associated symptoms in cancer patients undergoing chemotherapy. Spec.. Read More»