Sarah fahad alotaibi
Medicine, Saudi Arabia
Publications
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Research
The Impact of GERD on Middle Ear Health: A Systematic Review With Focus on Psychobehavioral Factors
Author(s): Sarah fahad alotaibi*, Salem Mansour Abokhanjar, Ghadi Salaiman Aljohani, Khaled Waleed Alomran, Rawan Ibrahim Sangoura, Abdullah Mfwadh Alanazi, Raghad Naif Matrouk Alotaibi, Abdalrahman T. Albader and Razan Abdullah AlQahtani
Background: Otitis Media with Effusion (OME) is a leading cause of hearing loss in children and a significant otologic concern in adults. Emerging research has proposed a potential pathophysiological link between gastroesophageal reflux disease (GERD) and OME, wherein refluxate reaches the middle ear, contributing to mucosal inflammation and fluid accumulation. Objective: This systematic review aims to evaluate the evidence for a clinical and mechanistic association between GERD and OME, assess the diagnostic utility of reflux biomarkers such as pepsin in middle ear effusions, and analyze the impact of GERD treatment on OME outcomes across Pediatric and adult populations. Methods: A systematic search of PubMed, Scopus, Cochrane Library, and Google Scholar was conducted for studies published from 2000 to 2025. Studi.. Read More»